The Centers for AIDS Research (CFAR) program at the National Institutes of Health provides administrative and shared research support to synergistically enhance and coordinate high quality AIDS research projects. CFARs accomplish this through core facilities that provide expertise, resources, and services not otherwise readily obtained through more traditional funding mechanisms.   The Case Western Reserve University/University Hospitals of Cleveland Center for AIDS Research is one of 20 CFARS located in the United States .   Case Western Reserve University/University Hospitals of Cleveland National Institutes of Health Grant:  AI36219.   For additional information on citing/acknowledging the Case/UHC CFAR, click here

 

CFAR ANNOUNCEMENTS

 

 

 

August 1, 2007.  The CFAR has leased an apartment to facilitate housing visiting scholars.  To find out more click here

 

June 21, 2007.  Drs. Whalen and Sethi receive 2 of 10 Doris Duke Foundation Awards to continue their AIDS-related research.  To find out more, click here.  

 

June 4, 2007.  The 2007-08 Case/UHC CFAR Development Awards have been awarded.  To find out more click here.

 

 

Article:  Predictive Value of Plasma HIV RNA Level on Rate of CD4 T-Cell Decline in Untreated HIV Infection, Rodriguez B, et. al.  Journal of the American Medical Association, 27 September 2006.  Click here for press release on article.

 

 

Announcement of Award.  Case Chemist, Dr. Mary Barkley, takes on HIV-1 virus with $1 million support from NIH. September 15, 2006.  Click here for article on award

 

 

Article: Microbicide Project: Prevention of Vaginal SHIV Transmission in Rhesus Macaques Through Inhibition of CCR5, Lederman, et.al., Science, 15 October 2004, click here.

 

 

The Case Western Reserve University/University Hospitals Center For AIDS Research (Case CFAR) has been continually funded since its initiation in April 1994 as one of 11 such centers of excellence established by the National Institutes of Health.  The CFAR has a mandate to coordinate basic and clinical research activities and to promote interdisciplinary research in HIV infection and AIDS.  Comprising more than 140 faculty researchers at the Schools of Medicine, Nursing, Arts and Sciences, and Law, the CFAR provides core resources, seminars, lectureships, publications and developmental funding to promote and strengthen the AIDS resarch programs at the University and its affiliated institutions.  CFAR membership includes scientist and clinicians from Case, University Hospitals of Cleveland, MetroHealth Medical Center, The Cleveland Veterans Administration Center and the Cleveland Clinic Foundation.  Current key areas of research strength include a) international aspects of AIDS; b) AIDS clinical research; c) HIV immunology; d) molecular virology; e) mycobacterial disease; f) AIDS-related malignancies; and g) HIV prevention.

 

 

 

 

 

 

Center for AIDS Research Grant Renewed With $8 Million Award from NIH

CLEVELAND -- The Case Western Reserve University/University Hospitals of Cleveland Center for AIDS Research (Case CFAR) announced that it has received a five-year grant from the National Institutes of Health, providing a 39 percent increase in funding over the CFAR’s previous award from the NIH.  The NIH award provides $8 million for CFAR operations.  Additionally, the NIH support provides the center with the opportunity to apply for supplemental funding each year for various AIDS-related projects.

Michael M. Lederman, M.D., director of the Case CFAR, responded to the receipt of the grant: “This renewal of our Center for AIDS Research is wonderful news. It represents recognition by the NIH of the strong AIDS research program at Case and UHC, and the hard work of the more than 130 AIDS researchers who comprise this center of excellence.  This five-year award will provide our researchers here and in Africa access to resources and facilities to speed the progress of their work.”

The Case CFAR provides clinical and technological support to researchers working on AIDS-related projects at Case, UHC, MetroHealth Medical Center, the Cleveland Clinic Foundation, and several international sites.  It is part of a program that was established by the NIH to promote collaboration between basic and clinical researchers on AIDS-related projects, emphasizing translational research in which findings from the laboratory are brought to the clinic and vice versa.  There are 21 such centers currently funded by the NIH.  The Case CFAR is the only one located in the Midwest.

“One of the positive benefits of the CFAR is the uniting of basic scientists working on AIDS with their clinical colleagues,” said Jonathan Karn, Ph.D., associate director of the CFAR. “With the Case School of Medicine rapidly expanding centers of excellence, such as the CFAR, Case will continue to become more attractive to the outstanding researchers we are actively recruiting.” 

Since its founding in 1994, the Case CFAR has been dedicated to coordinating an ever-expanding spectrum of AIDS-related activities.  Major strengths of the Case CFAR include clinical and translational research, international research, and in training young researchers, both on a national and international level.  In Cleveland, a close, dynamic relationship between the CFAR and the NIH-funded AIDS Clinical Trials Unit (a collaboration between UHC, MetroHealth, and the Cleveland Clinic), assists in fulfilling these institutions’ mandates as centers of excellence and providers of the highest quality patient care.  On the international front, a long-standing scientific relationship with Makerere University in Kampala, Uganda, has culminated in establishing sophisticated CFAR laboratories in Uganda, providing support for AIDS-related research in Africa.

The Case CFAR works actively with other Case centers and departments in areas of mutual interest. In addition to the AIDS Clinical Trials Unit, these include the Comprehensive Cancer Center (AIDS–related malignancies, studies of immune restoration), the Tuberculosis Research Unit (TBRU, HIV/TB interactions), the Skin Diseases Research Center’s Center for Medical Mycology (CMM-opportunistic fungal infections), the Center for Global Health and Disease (international research), the EpID Center (epidemiology/biostatistics, international research), and the Department of  Biomedical Ethics and the Law-Medicine Center (Ethics of AIDS Research and Care Research Program). 

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CITATION OF THE CASE/UHC CENTER FOR AIDS RESEARCH

 Researchers who utilize Case/UHC Center for AIDS Research services, 

are strongly encouraged to cite the CFAR in all publications 

resulting from the use of the services. 

 Case/UHC Center for AIDS Research

NIH Grant Number: AI36219

Electronic copies of the Case/UHC CFAR logo can be obtained by contacting Bob Bucklew at rob2@case.edu or 216.844.2247; or

Mary Robertson at robertson.mary@clevelandactu.org  or 216.844.2342

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